Medical Education

Play this short video to delve deeper into the pathophysiology of PSP and the mechanism of action of FNP-223.
Available in English & Spanish!​
 Remember to click the “full screen” button for a better experience.

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FNP-223 Infographic

Learn about the FNP-223 mechanism of action(MoA)​ in a schematic and visual way.

Image of the abstract of OGA inhibition study
OGA inhibition as a novel therapeutic approach for tauopathies

Discover how targeting the O-GlcNAcylation pathway through selective OGA inhibition (FNP-223), offers a compelling disease-modifying strategy for PSP.
The publications contained in this section are subject to congress copyright permissions.

Clinical Trials & Publications

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PROSPER Study

Navigate through the trial website to learn more about the eligibility criteria, endpoints and sites around US, UK and Europe.

Image of the abstract of PROSPER study
Design of a Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study with FNP-223 (oral formulation) in PSP: The PROSPER Study

Read more about the PROSPER study protocol design.
The publications contained in this section are subject to congress copyright permissions.

Congresses & Events

AD/PD 2025

Learn more about the therapeutic potential of OGA inhibition as a treatment for progressive supranuclear palsy and the FNP-223 development program!​

Patient-Focused Initiatives

Stay Informed About Patient-Led Efforts in PSP Awareness, Care and Research

Explore resources and activities spearheaded by patient associations to foster early diagnosis, disease understanding, and drive progress in research. These initiatives provide healthcare professionals with insights into how patients and caregivers are being supported, enabling you to guide them effectively through every stage of their journey.

Navigating PSP - From Early Symptoms and Trials

Dr. Anne-Marie Wills discusses the early symptoms of PSP, its underlying physiology, and the importance of early diagnosis. She also explains how clinical trials work, the benefits of participating early in the disease, and how they can help advance PSP treatment.​

Introduction to the PROSPER Trial

Dr. Günter Höglinger introduces the PROSPER Trial, a Phase 2 clinical trial for PSP. Learn about the investigational drug being tested, trial eligibility and design and how participation could help further PSP research and treatment development.

Let's demystify PSP